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Partner, Research, Solve, Change: Driving Progress in Health Globally.

About the Initiative

The Change Initiative is a pioneering initiative convened by the Office of Health Economics (OHE), an Independent Research Organisation (IRO) and registered not-for-profit, leveraging the collective expertise and insights of an expanding community of the world’s leading organisations in health and care.

Unique in its ability to bring industry, civil society and academia together, the Change Initiative is addressing critical global health challenges.

The world-leading team at OHE have been doing this for over 60 years through focused research programmes with the health sector.

Our Vision

A future where the interplay of social, economic, and environmental factors creates healthier, fairer, and more resilient communities worldwide.

Our Mission

To respond to the complex and multifaceted nature of health challenges through collaborative global action and the innovative application of research.

Why The Initiative Exists

Addressing System-Level Challenges

The Initiative targets complex inefficiencies and inequalities in global health systems for long-term value.​

Collaborative Multisector Approach

It convenes diverse stakeholders to develop shared, evidence-based solutions beyond traditional boundaries.​

Vision for Resilient Health Systems​

The Initiative envisions resilient, equitable, and sustainable health systems through innovation and prevention.​

Supporting Timely Policy Adoption

It combines research, expert guidance, and dissemination to enable real-world health policy reforms.​

The decisions being made about healthcare today will shape the health of populations for decades to come.

No single organisation can answer them alone. That is precisely why we founded the Change Initiative.

View our Current Projects

The Change Initiative currently brings together leading organisations from across industry, academia, and civil society to address two of the most pressing challenges in global health policy.

Our US Policy Horizon Series is examining how landmark American pricing reforms, from the Inflation Reduction Act to the Most Favored Nation policy, are reshaping pharmaceutical innovation and access worldwide.

Our Financing Prevention programme is tackling the persistent underinvestment in preventive health, developing actionable models that can shift resources upstream before illness takes hold.

Both programmes are grounded in independent, evidence-led research, designed not just to inform debate, but to change it.

View our projects

Explore Our Latest Work

From promise to practice: Addressing the systemic challenges of underinvestment in prevention

A sustainable approach to prevention financing requires selecting a combination of mechanisms that are most appropriate for local contexts…

Most Favored Nation pricing: What it means for policy, patients and pharma

President Trump says the rest of the world is free-riding on American pharmaceutical prices. But what will substantial policy change mean for patients in the US and around the world?

Contact us

Whether you are interested in exploring a potential partnership, looking to contribute expertise as part of our Expert Council, or simply want to find out more about our work, we would love to hear from you.

Contact Us